How the camel got his hump

HOW THE NONCENTRAL t DISTRIBUTION GOT ITS HUMP

Once upon a time there was only one t distribution, the familiar central t, and it was monopolised by the Null Hypotheses (the Nulls), the high priests in Significance Land. The Alternative Hypotheses (the Alts) felt unjustly neglected, so they developed the noncentral t distribution to break the monopoly, and provide useful functions for researchers—calculation of statistical power, and confid...

How the Camel Lost Its Hump: The Impact of Object Typicality on Event-related Potential Signals in Object Decision

Using an object decision task, event-related potentials (ERPs), and minimum norm current source estimates, we investigated early spatiotemporal aspects of cortical activation elicited by line drawings that were manipulated on two dimensions: authenticity and typicality. Authentic objects were those that match real-world experience, whereas nonauthentic objects were "doctored" by deletion or add...

How the Pufferfish Got His Spikes: Neurotoxicity in Sodium Channel Blockers

When man got his mtDNA deletions?

Somatic mtDNA mutations and deletions in particular are known to clonally expand within cells, eventually reaching detrimental intracellular concentrations. The possibility that clonal expansion is a slow process taking a lifetime had prompted an idea that founder mutations of mutant clones that cause mitochondrial dysfunction in the aged tissue might have originated early in life. If, converse...

How I got over the Christmas flu.